Spinraza is a prescription medication approved by the U.S. Food and Drug Administration (FDA) for treating spinal muscular atrophy (SMA) in children and adults. Spinraza is also known by its drug name, Nusinersen.1
People with SMA don’t produce enough of a substance called survival motor neuron (SMN) protein, which is important for healthy motor functioning.2 Spinraza is believed to work by increasing the body’s production of SMN protein.2
How do I take it?
Spinraza is administered intrathecally, which means it’s injected into the fluid surrounding the spinal cord. After three loading doses at 14-day intervals, the fourth is administered 30 days later. After the fourth loading dose, maintenance doses are given once every four months.1
The FDA-approved label for Spinraza lists common side effects including respiratory infections and constipation in babies with SMA. Fever, headache, vomiting, and back pain may be experienced in people with later-onset of SMA.1
Rare but serious side effects listed for Spinraza can include increased risk of bleeding and kidney damage or failure.1
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